A highly stereoselective synthesis of β-trifluoromethylated homoallylic alcohols in water

T. P. Loh, X. R. Li

科研成果: 期刊稿件文章同行评审

75 引用 (Scopus)

摘要

A tin-mediated, indium trichloride promoted allylation reaction provided β-trifluoromethylated homoallylic alcohols, the building blocks of biologically active substances, in high yields and excellent stereoselectivity. Since the syntheses can be carried out in water, the reactive OH groups do not need to be protected, and even compounds that are insoluble in organic solvents can be used.

源语言英语
页(从-至)980-982
页数3
期刊Angewandte Chemie - International Edition
36
9
DOI
出版状态已出版 - 1997
已对外发布

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