摘要
A tin-mediated, indium trichloride promoted allylation reaction provided β-trifluoromethylated homoallylic alcohols, the building blocks of biologically active substances, in high yields and excellent stereoselectivity. Since the syntheses can be carried out in water, the reactive OH groups do not need to be protected, and even compounds that are insoluble in organic solvents can be used.
源语言 | 英语 |
---|---|
页(从-至) | 980-982 |
页数 | 3 |
期刊 | Angewandte Chemie - International Edition |
卷 | 36 |
期 | 9 |
DOI | |
出版状态 | 已出版 - 1997 |
已对外发布 | 是 |