Aldol reaction under solvent-free conditions: Highly stereoselective synthesis of 1,3-amino alcohols

Teck Peng Loh, Jing Mei Huang, Swee Hock Goh, Jagadese J. Vittal

科研成果: 期刊稿件文章同行评审

63 引用 (Scopus)

摘要

(formula presented) A method for the highly stereoselective synthesis of 1,3-amino alcohols based on the indium trichloride-catalyzed Mukaiyama aldol reaction of keto ester (R,S)-1 under solvent-free conditions has been developed. The high selectivity observed can be explained on the basis of the shielding of one face by a remote substituent.

源语言英语
页(从-至)1291-1294
页数4
期刊Organic Letters
2
9
DOI
出版状态已出版 - 4 5月 2000
已对外发布

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