摘要
A simple and practical method to access N-substituted 2-pyridones via a formal [3+3] annulation of enaminones with acrylates based on RhIII-catalyzed C-H functionalization was developed. Control and deuterated experiments led to a plausible mechanism involving C-H bond cross-coupling and aminolysis cyclization. This strategy provides a short synthesis of structural motifs of N-substituted 2-pyridones.
源语言 | 英语 |
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页(从-至) | 15020-15023 |
页数 | 4 |
期刊 | Chemical Communications |
卷 | 56 |
期 | 95 |
DOI | |
出版状态 | 已出版 - 11 12月 2020 |