Design, syntheses and biological evaluation of 5-fluoroindolin-2-one derivatives with urea linkage

Baohua Zou, Zheng Fang, Zhao Yang, Kai Guo

科研成果: 书/报告/会议事项章节会议稿件同行评审

摘要

Nine 5-fluoroindolin-2-one derivatives with urea linkage were designed and synthesized. The obtained structures were identified by 1H NMR, MS and elemental analysis. In vitro evaluation of antitumor bioactivity was performed by MTT method. Most of synthesized compounds showed antitumor activities, especially, compounds 6e and 6f, which were better than or equal to the antitumor activity of positive control.

源语言英语
主期刊名Advances in Chemical, Material and Metallurgical Engineering
926-929
页数4
版本1
DOI
出版状态已出版 - 2013
活动2012 2nd International Conference on Chemical, Material and Metallurgical Engineering, ICCMME 2012 - Kunming, 中国
期限: 15 12月 201216 12月 2012

出版系列

姓名Advanced Materials Research
编号1
634-638
ISSN(印刷版)1022-6680

会议

会议2012 2nd International Conference on Chemical, Material and Metallurgical Engineering, ICCMME 2012
国家/地区中国
Kunming
时期15/12/1216/12/12

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