Electrosynthesis of Spiro-indolenines via Dearomative Arylation of Indoles in Batch and Continuous Flow

Wei Zhao; Yi Lu; Yaqi Qiao; Xing Yin; Chengkou Liu; Zheng Fang; Jianliang Zhu; Kai Guo

doi:10.1021/acs.orglett.3c03149

Electrosynthesis of Spiro-indolenines via Dearomative Arylation of Indoles in Batch and Continuous Flow

Wei Zhao, Yi Lu, Yaqi Qiao, Xing Yin, Chengkou Liu, Zheng Fang, Jianliang Zhu, Kai Guo

生物与制药工程学院

科研成果: 期刊稿件 › 文章 › 同行评审

8 引用（Scopus）

摘要

An electrosynthesis of spiro-indolenines in batch and continuous flow was achieved through dearomative arylation of indoles with good functional group compatibility. User-friendly undivided cells were used under catalyst- and oxidant-free conditions. Moreover, the use of a flow electrolysis cell gave high daily productivity and excellent scale-up potential under less supporting electrolyte and higher substrate concentration conditions.

源语言	英语
页（从-至）	7451-7456
页数	6
期刊	Organic Letters
卷	25
期	40
DOI	https://doi.org/10.1021/acs.orglett.3c03149
出版状态	已出版 - 13 10月 2023

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abstract = "An electrosynthesis of spiro-indolenines in batch and continuous flow was achieved through dearomative arylation of indoles with good functional group compatibility. User-friendly undivided cells were used under catalyst- and oxidant-free conditions. Moreover, the use of a flow electrolysis cell gave high daily productivity and excellent scale-up potential under less supporting electrolyte and higher substrate concentration conditions.",

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AU - Zhao, Wei

AU - Lu, Yi

AU - Qiao, Yaqi

AU - Yin, Xing

AU - Liu, Chengkou

AU - Fang, Zheng

AU - Zhu, Jianliang

AU - Guo, Kai

PY - 2023/10/13

Y1 - 2023/10/13

N2 - An electrosynthesis of spiro-indolenines in batch and continuous flow was achieved through dearomative arylation of indoles with good functional group compatibility. User-friendly undivided cells were used under catalyst- and oxidant-free conditions. Moreover, the use of a flow electrolysis cell gave high daily productivity and excellent scale-up potential under less supporting electrolyte and higher substrate concentration conditions.

AB - An electrosynthesis of spiro-indolenines in batch and continuous flow was achieved through dearomative arylation of indoles with good functional group compatibility. User-friendly undivided cells were used under catalyst- and oxidant-free conditions. Moreover, the use of a flow electrolysis cell gave high daily productivity and excellent scale-up potential under less supporting electrolyte and higher substrate concentration conditions.

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JO - Organic Letters

JF - Organic Letters

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ER -

Electrosynthesis of Spiro-indolenines via Dearomative Arylation of Indoles in Batch and Continuous Flow

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