Indium(III) iodide-mediated Strecker reaction in water: an efficient and environmentally friendly approach for the synthesis of α-aminonitrile via a three-component condensation

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摘要

A mild, efficient and environmentally friendly method has been developed for the synthesis of α-aminonitriles via a three-component condensation of aldehyde, amine and TMSCN in the presence of a catalytic amount of indium(III) iodide in water. The reactions proceeded smoothly at room temperature in water to generate the corresponding products in moderate to excellent yields.

源语言英语
页(从-至)8159-8163
页数5
期刊Tetrahedron
64
35
DOI
出版状态已出版 - 25 8月 2008
已对外发布

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