Insight into a direct solid-solid transformation: A potential approach for the removal of residual solvents

Pengpeng Yang, Chenguang Lin, Wei Zhuang, Qingshi Wen, Fengxia Zou, Jingwei Zhou, Jinglan Wu, Hanjie Ying

科研成果: 期刊稿件文章同行评审

14 引用 (Scopus)

摘要

Here we report two new crystal forms of adenosine 3′,5′-cyclic monophosphate sodium and the discovery of the direct solid-solid transformation process from its methanol trihydrate (solvate) to its pentahydrate form (hydrate) that is only mediated by humidity. These findings provide a potential approach for the removal of residual solvents in the manufacturing of pharmaceuticals and food additives.

源语言英语
页(从-至)1699-1704
页数6
期刊CrystEngComm
18
10
DOI
出版状态已出版 - 2016

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