Macrolide Synthesis through Intramolecular Oxidative Cross-Coupling of Alkenes

Bing Jiang, Meng Zhao, Shu Sen Li, Yun He Xu, Teck Peng Loh

科研成果: 期刊稿件文章同行评审

83 引用 (Scopus)

摘要

A RhIII-catalyzed intramolecular oxidative cross-coupling between double bonds for the synthesis of macrolides is described. Under the optimized reaction conditions, macrocycles containing a diene moiety can be formed in reasonable yields and with excellent chemo- and stereoselectivity. This method provides an efficient approach to synthesize macrocyclic compounds containing a 1,3-conjugated diene structure.

源语言英语
页(从-至)555-559
页数5
期刊Angewandte Chemie - International Edition
57
2
DOI
出版状态已出版 - 8 1月 2018

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