Microfluidic synthesis of pyrrolidin-2-onesviaphotoinduced organocatalyzed cyclization of styrene, α-bromoalkyl esters and primary amines

Minghui Wei, Jingming Zhang, Chengkou Liu, Wei He, Tingyu Wang, Xiaobing Yang, Zhao Yang, Zheng Fang, Kai Guo

科研成果: 期刊稿件文章同行评审

9 引用 (Scopus)

摘要

A green and efficient reaction route for the synthesis of pyrrolidin-2-onesviaphotoinduced organocatalyzed three-component cyclization of styrene, tertiary α-bromoalkyl esters and primary amines in a microchannel reactor under visible light conditions has been developed. Moreover, the overall process can be carried out under mild conditions without using a metal. In addition, a reasonable reaction mechanism was proposed based on control experiments.

源语言英语
页(从-至)6468-6472
页数5
期刊Organic and Biomolecular Chemistry
19
29
DOI
出版状态已出版 - 7 8月 2021

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