New carbazole fluorescent sensor for ultrasensitive and ratiometric sensing of SO₂ derivatives and hydrazine

The probe CBTA is a novel bifunctional fluorescent probe that can detect bisulfite and hydrazine hydrate in a rational manner. And probe CBTA could specifically detect bisulfite and hydrazine hydrate among different analytes. Moreover, the response time of probe CBTA to SO₂ derivatives and hydrazine is extremely short, and the detection limits for bisulfite and hydrazine are as low as 5.6 nmol and 39 nmol. Cellular experiments also indicated that the probe CBTA was low in cytotoxicity and could be applied to cellular fluorescence imaging. Therefore, the probe CBTA could provide an efficient means for detecting SO₂ derivatives and hydrazine in vitro.