New potential inhibitors of DNA topoisomerase. Part II: Design and synthesis of α-lapachone derivatives under microwave irradiation

Ping Wei, Xiaohong Zhang, Shujiang Tu, Shu Yan, Hanjie Ying, Pingkai Ouyang

科研成果: 期刊稿件文章同行评审

42 引用 (Scopus)

摘要

A new series of potential inhibitors of DNA topoisomerase II were synthesized from facile materials (aromatic aldehydes, Meldrum's acid and 2-hydroxynaphthalene-1,4-dione) under microwave irradiation. The method provides a valuable tool in designing new and more potent cytotoxic analogues. This procedure is advantageous both economically and environmentally.

源语言英语
页(从-至)828-830
页数3
期刊Bioorganic and Medicinal Chemistry Letters
19
3
DOI
出版状态已出版 - 1 2月 2009

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