Palladium-Catalyzed Direct C-H Trifluoroethylation of Aromatic Amides

Manikantha Maraswami, Sreekumar Pankajakshan, Gang Chen, Teck Peng Loh

科研成果: 期刊稿件文章同行评审

40 引用 (Scopus)

摘要

A simple and direct C-H trifluoroethylation of aromatic amides has been developed. The protocol is applicable to a variety of aromatic amides, including ones derived from amino acids. The developed method can be used for further modifications of peptides. Preliminary mechanistic studies have been done by isolating the reaction intermediate.

源语言英语
页(从-至)4223-4226
页数4
期刊Organic Letters
19
16
DOI
出版状态已出版 - 18 8月 2017

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