Regioselective and Stereoselective Difluoromethylation of Enamides with Difluoromethyltriphenylphosphonium Bromide via Photoredox Catalysis

Tong Hao Zhu, Ze Yu Zhang, Ji Yu Tao, Kai Zhao, Teck Peng Loh

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70 引用 (Scopus)

摘要

A regioselective and stereoselective difluoromethylation of enamides with bench-stable and easily accessible difluoromethyltriphenylphosphonium bromide is described. A broad array of synthetically important and geometrically defined β-difluoromethylated enamides bearing various functional groups are obtained with up to 91% yield.

源语言英语
页(从-至)6155-6159
页数5
期刊Organic Letters
21
15
DOI
出版状态已出版 - 2 8月 2019

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