Synthesis of Mono-fluoroallenes through Copper-Catalyzed Defluorinative Silylation of α,α-Difluoroalkylalkynes

Luning Tang, Bing Bing Pei, Yang Song, Fei Xue, Yanni Yue, Chao Feng

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4 引用 (Scopus)

摘要

A straightforward protocol for the synthesis of mono-fluorinated allenes via catalytic defluorinative silylation of the readily available α,α-difluoroalkylalkynes with commercially available copper catalyst and phosphine ligand is described. A broad scope of α,α-difluoroalkylalkynes were well accommodated and a gram-scale synthesis demonstrated the synthetic utility of this methodoglogy.

源语言英语
页(从-至)2035-2039
页数5
期刊Chinese Journal of Chemistry
40
17
DOI
出版状态已出版 - 1 9月 2022

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