Synthesis of pyrido[1,2-a]indol-6(7H)-ones via a visible light-photocatalyzed formal (4 + 2) cycloaddition of indole-derived bromides and alkenes or alkynes

Minghui Wei, Chengkou Liu, Chang Sheng Wang, Yuguang Li, Peng Qiu, Quanxiao Dong, Zhao Yang, Zheng Fang, Kai Guo

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7 引用 (Scopus)

摘要

We successfully developed an unprecedented synthesis route to pyrido[1,2-a]indol-6(7H)-ones through a visible light-photocatalyzed formal (4 + 2) cycloaddition of indole-derived bromides and alkenes or alkynes in a microchannel reactor. This novel protocol features extremely mild conditions, a broad substrate scope and high reaction efficiency. In addition, a reasonable reaction mechanism based on controlled experiments was proposed.

源语言英语
页(从-至)2453-2457
页数5
期刊Green Chemistry
25
6
DOI
出版状态已出版 - 10 3月 2023

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