Total synthesis of phytophthora mating hormone α1

Shun Yi Wang; Ping Song; Li Yan Chan; Teck Peng Loh

doi:10.1021/ol102177j

Total synthesis of phytophthora mating hormone α1

Shun Yi Wang, Ping Song, Li Yan Chan, Teck Peng Loh

Nanyang Technological University

科研成果: 期刊稿件 › 文章 › 同行评审

18 引用（Scopus）

摘要

Total synthesis of Phytophthora mating hormone α1 (1) has been demonstrated. The required stereochemistries (methyl) are achieved by applying CuI-(S)-Tol-BINAP-catalyzed conjugate addition of Grignard reagents to α,β-unsaturated esters.

源语言	英语
页（从-至）	5166-5169
页数	4
期刊	Organic Letters
卷	12
期	22
DOI	https://doi.org/10.1021/ol102177j
出版状态	已出版 - 19 11月 2010
已对外发布	是

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10.1021/ol102177j

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title = "Total synthesis of phytophthora mating hormone α1",

abstract = "Total synthesis of Phytophthora mating hormone α1 (1) has been demonstrated. The required stereochemistries (methyl) are achieved by applying CuI-(S)-Tol-BINAP-catalyzed conjugate addition of Grignard reagents to α,β-unsaturated esters.",

author = "Wang, {Shun Yi} and Ping Song and Chan, {Li Yan} and Loh, {Teck Peng}",

year = "2010",

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AU - Wang, Shun Yi

AU - Song, Ping

AU - Chan, Li Yan

AU - Loh, Teck Peng

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N2 - Total synthesis of Phytophthora mating hormone α1 (1) has been demonstrated. The required stereochemistries (methyl) are achieved by applying CuI-(S)-Tol-BINAP-catalyzed conjugate addition of Grignard reagents to α,β-unsaturated esters.

AB - Total synthesis of Phytophthora mating hormone α1 (1) has been demonstrated. The required stereochemistries (methyl) are achieved by applying CuI-(S)-Tol-BINAP-catalyzed conjugate addition of Grignard reagents to α,β-unsaturated esters.

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U2 - 10.1021/ol102177j

DO - 10.1021/ol102177j

M3 - 文章

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SN - 1523-7060

VL - 12

SP - 5166

EP - 5169

JO - Organic Letters

JF - Organic Letters

IS - 22

ER -

Total synthesis of phytophthora mating hormone α1

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