摘要
The super organoreductant CBZ6-catalyzed tandem transalkylation-cyclization using amines as traceless radical donors and stabilizer is reported. The later-stage breaking of an N-C bond enables the transalkylation with a secondary amine as the leaving moiety. A wide range of tertiary amines were used as alkyl radical donors for the C1-C8 alkyls. This traceless stabilizer also enabled the transalkylation with methyl radical, which is normally not possible because of the instability of methyl radical.
源语言 | 英语 |
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页(从-至) | 7518-7522 |
页数 | 5 |
期刊 | Organic Letters |
卷 | 25 |
期 | 41 |
DOI | |
出版状态 | 已出版 - 20 10月 2023 |