Copper-catalyzed three-component cyclization of amidines, styrenes, and fluoroalkyl halides for the synthesis of modular fluoroalkylated pyrimidines

Xue Qiang Chu, Bu Qing Cheng, Yao Wei Zhang, Danhua Ge, Zhi Liang Shen, Teck Peng Loh

科研成果: 期刊稿件文章同行评审

60 引用 (Scopus)

摘要

An efficient copper-catalyzed three-component cyclization for the construction of highly functionalized pyrimidine derivatives from readily available amidines, styrenes and fluoroalkyl halides is developed. This protocol distinguishes itself by the formation of three new C-C/C-N bonds and a new six-membered ring through a radical addition/oxidation/cyclization sequence in a one-pot manner.

源语言英语
页(从-至)2615-2618
页数4
期刊Chemical Communications
54
21
DOI
出版状态已出版 - 2018

指纹

探究 'Copper-catalyzed three-component cyclization of amidines, styrenes, and fluoroalkyl halides for the synthesis of modular fluoroalkylated pyrimidines' 的科研主题。它们共同构成独一无二的指纹。

引用此