@article{444963eae36741bc9ab9167f7f0f9e70,
title = "Engineering Melanin Nanoparticles as an Efficient Drug-Delivery System for Imaging-Guided Chemotherapy",
abstract = "In order to promote imaging-guided chemotherapy for preclinical and clinical applications, endogenous nanosystems with both contrast and drug-delivery properties are highly desired. Here, the simple use of melanin is first reported, and this biopolymer with good biocompatibility and biodegradability, binding ability to drugs and ions, and intrinsic photoacoustic properties, can serve as an efficient endogenous nanosystem for imaging-guided tumor chemotherapy in living mice.",
keywords = "drug delivery, melanin nanoparticles, photoacoustic imaging, positron emission tomography (PET), sorafenib",
author = "Ruiping Zhang and Quli Fan and Min Yang and Kai Cheng and Xiaomei Lu and Lei Zhang and Wei Huang and Zhen Cheng",
note = "Publisher Copyright: {\textcopyright} 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.",
year = "2015",
month = sep,
day = "1",
doi = "10.1002/adma.201502201",
language = "英语",
volume = "27",
pages = "5063--5069",
journal = "Advanced Materials",
issn = "0935-9648",
publisher = "Wiley-Blackwell",
number = "34",
}