Iron(0)-Mediated Reformatsky Reaction for the Synthesis of β-Hydroxyl Carbonyl Compounds

Xuan Yu Liu, Xiang Rui Li, Chen Zhang, Xue Qiang Chu, Weidong Rao, Teck Peng Loh, Zhi Liang Shen

科研成果: 期刊稿件文章同行评审

21 引用 (Scopus)

摘要

An efficient, economical, and practical Reformatsky reaction of α-halo carbonyl compounds with aldehydes/ketones by using cheap and commercial iron(0) powder as reaction mediator is developed. The reactions proceeded effectively in the presence of a catalytic amount of iodine (20 mol %) to afford the synthetically useful β-hydroxyl carbonyl compounds in moderate to good yields.

源语言英语
页(从-至)5873-5878
页数6
期刊Organic Letters
21
15
DOI
出版状态已出版 - 2 8月 2019

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