Synthesis of hydrochloric 6-guandinyl hexanoic acid

Jin Feng Yao, Wen Ge Yang, Lei Shen, Xiao Lei Zhao, Xiu Tao Lu, Yong Hong Hu

科研成果: 期刊稿件文章同行评审

摘要

Hydrochloric 6-guandinyl hexanoic acid is synthesized from caprolactam by the hydrolization to give 6-aminohexanoic acid which is subjected to reaction with S-methylisothioureasulfate to obtain 6-guandinyl hexanoic acid, then reacted with dilute hydrochloric acid followed by 6-guandinyl hexanoic acid salt formation. The method has been improved in the process of synthesis of 6-aminocaproic and 6-guandinyl hexanoic acid and the total yield can be increased to 70.4%.

源语言英语
页(从-至)57-58
页数2
期刊Xiandai Huagong/Modern Chemical Industry
29
7
出版状态已出版 - 7月 2009

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